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Treatments Neutropenia is characterized by a significant reduction in neutrophils, a type of white blood cell that is an essential first line of defense against infections. The main complication of neutropenia is an increased risk of infection.
Neutrophils are made in the bone marrow. They are short-lived cells that travel extensively throughout the body and can enter tissues other cells cannot. Most commonly, cancer patients develop neutropenia due to chemotherapy. The drugs involved destroy the neutrophils along with the cancer cells they are designed to kill.
In this article, we will discuss the causes, symptoms, and treatments of neutropenia. Fast facts on neutropenia Here are some key points about neutropenia.
More detail and supporting information is in the main article. In health, neutrophils are the most abundant type of white blood cell. One of the most common causes of neutropenia is chemotherapy. Often, there are no particular symptoms other than a heightened risk of infection.
Febrile neutropenia is regarded as a medical emergency. Individuals with neutropenia must take extra precautions to avoid infection.
Neutropenia describes a reduction in neutrophils. Neutropenia is a condition where there are abnormally low levels of neutrophils in the blood supply. Neutrophils are an important type of white blood cell, vital for fighting off pathogens, particularly bacterial infections.
In adults, a count of 1, neutrophils per microliter of blood or less is considered to be neutropenia, with any count below per microliter of blood regarded as a severe case. In severe cases, even bacteria that are normally present in the mouth, skin, and gut can cause serious infections.
Neutropenia can be due to a decrease in neutrophil production, accelerated usage of neutrophils, increased destruction of neutrophils, or a combination of all three factors. Neutropenia can be temporary acute or long-lasting chronic. The condition is also split into congenital present from birth and acquired neutropenia develops later in life.
Types There is a range of neutropenias, including: This is a rare congenital syndrome causing fluctuations in neutrophil numbers, it affects an estimated 1 in 1, people. This is a genetic disorder where neutrophils are produced at lower levels. People with Kostmann's syndrome are prone to infections from an early age.
This is a relatively common version of neutropenia, predominantly affecting women. This is a condition in which neutrophils fail to move from the bone marrow where they are created to the bloodstream. This occurs when an individual's immune system attacks and destroys neutrophils.
This is a rare genetic disorder with multiple effects including dwarfismproblems with the pancreas, and a low neutrophil count. This is a condition where a mother's antibodies cross the placenta and attack the developing fetus' neutrophils.
This condition generally resolves itself within 2 months of life. It can be asymptomatic or result in sepsis. Causes Neutrophils are produced in the bone marrow at the center of larger bones.
Anything that disrupts this process can cause neutropenia.Williams Syndrome is a rare genetic disorder which leads to developmental problems, such as: a child’s growth, physical appearance and cognitive development. This syndrome is .
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